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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22cc5e8d69c2841cf9938b03e9e8fe58893224ce58bb3b65412b74aca0dd9f86' 
  AND token = 'OZyn9DobsavPMGXju/D5iL9ZO2BS94Tn8+ihfj+4vIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}