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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c29fedea27b5bf105c0579c5be975200681b9881677b73081eb55c4413e414a' 
  AND token = 'MN5zqzLkCEXAmQFt9TIfPxGf8fnv+sXWvgJKiW4i6b4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}