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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bd21a5ac6d7180885a22284f1a187bc9a1c6a1ab72549eb558cf05a784aba09' 
  AND token = 'c+zQf6XkJvE7ckFmHfVSAHSX7X2kGlECz+XtieAUQhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}