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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f278907024fd4571c97281a4aac62cd239c9e1b3460326455d95b7726486017' 
  AND token = 'AbOzeDVe5jk41DiyV06eV+HwCMtt4tFA5wUm6blegBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}