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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2d615ee703f76f7886803368a5edccb44bcb0fdab711ac21ad35348b5b234f4' 
  AND token = 'rEtA+czYMogC0ZVNkQbjD+OW6N1eUQ8g2RJsOPimkaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}