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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a3697f730a21675d55f6b7d31640c12d7a3f852823809e2b2ffdc9d8cf9c476' 
  AND token = 'Tse5mJ0W5zIdXE0ERRCUX9QgCy1Fi1dF8f93rV0dwq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}