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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae008b4c9be595e0955068f159fbb3ae6d242eded925f6d4cf3669b0da733828' 
  AND token = 'wWDKA10o5w7xl+L8qsb3TByTc0fdU69xaiHGJQxhWRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}