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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19fe5a1cba9f91febf0334b67f2b61d670cf452737c8c5bd2e453ebe9b933929' 
  AND token = 'A6uIX4QTmtJsdBMpTXkUJcCypJykIs0CKbw6G+usWMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}