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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a6785231c04d69e510c7e76ef50a426c1ab72bab735a98e2f8ef14eda240074' 
  AND token = 'ahL1QxPy8aI1x/iMuw+3vp36QM4/Mfh+wQdb9j3mt2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}