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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6498c3b3ce190d6c754858d063bcf79e510fb6fb7d044261faf56ba7b467b6a2' 
  AND token = 'U5NuM8T2VniogFDYl6bqluoTpPfazFSrtMsnYJuVYdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}