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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8427de631976929b42a8c915b992b80a003f7314fdb94f6695f6518821aeb5c3' 
  AND token = 'Vq7V+11QqtsG0ziEl3EL3MoRc5CVt/DqJimUaPeJIDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}