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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b429d18194b981cba1fce94b89819a24f04de8b9bacfee8c3ee4769a8c2ad9d0' 
  AND token = 'zLIhE0cfeyZLhoAOmigq/3DHe+QyTCNEk89C7Wo0M9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}