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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '554071e8b72fb19b04f41e20b128a905aef6e26c42f8554b5948e9e7334c42ea' 
  AND token = '1zwiQwzp1hMgAayqtbmIQSuCbt5Z25Cev6WZ2x+hAHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}