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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4ab79acca722515aa43bacdef36f080b9afa6f41e4e70934957073a47c6cae3' 
  AND token = 'PdtA72Cy3Hal7wP3iu/X+aQ/A060Hah6lv0tSMUrQyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}