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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14dfaa68685fea044e659a150a7c1d29385fc78b328870e1e84da2c938c169c5' 
  AND token = 'L19aNeADI96SfaJYBuCiYfxx/Q9auKpjeezuUPUOFYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}