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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86be58295533fcf01d88e32bff44330fe6037c21f8a4443012c2215ab5382b9c' 
  AND token = 'AcxubUCSxUzbnQM2QT3d4umOZr9XsjB+PIBfq8tAxgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}