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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37d50f9bedc41bc9b87c1f0c65749fed26a88658556d58a02baf242a57c3e315' 
  AND token = '9EKdmJWTqlyV1gW5UTY1elbSWXfOwJerWIBx38/Ky94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}