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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2bf633de8b04d1c7e076934c2491a5ac4b250001f24bf9af7cc7c1239bead61' 
  AND token = 'NoiuP4n6xaY6yGHvki9qwoaO/xZ73vkv9UMfgTskPz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}