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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d53f0754b87336959fe17e78622de7b5f1b71e14498ceb89c4775c36ace4a31' 
  AND token = 'KUhuRxR00y3WVGbk2r324wneK9GfsM2mlyP58GYs608=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}