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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'deff2b4152f54156f1fa0c3a4de75eac857bd1a96cfec927458f356ac9081050' 
  AND token = '54ElCydPjMbzSaD1vPu486BEEWxFRH1Vvrn2aDhbbZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}