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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1ef829d5c13d7d9015f9574344b8df6ac43c53736915c3b86d7674bc70eb08b' 
  AND token = 'AcKPnrBvNliu4xqxz786JRdj9WN24QCWGyNe0NHW8Wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}