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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df132bdd3b72880edba2407a90778138d41d30f8bcd0b8de71d2cbb1a59bc00c' 
  AND token = 'cgxYbsC2crNoLEHg5JWhzk7LCDIE0x/+qbM/v0bNz7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}