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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f22b985c9842691861880266ff6e99fa541f14563c7264db6e048af5598503ba' 
  AND token = 'JcX3u2KwwOz1iMBVBJtraWIXLAwf6r3mNxgqMMb9RAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}