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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65e4283d099eb81e0fc753a6e608f5382f53c34343062b3729ff5fb1d26c54db' 
  AND token = 'x7tp35+1b+el3DWQoksdwOyCpMVkaILjSs46CinHfoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}