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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6513183c1c5cf089239c59f039eece5b2e9f9a2b32ec09217101d7b003e4597' 
  AND token = '+Jc8tdobYJgBhZV19JgjIZwP6+StPM+4X6Akn+Ncclk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}