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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5631f22b6eed8b915799f8edd02bdad578b6e3a9307a3a2bb699cc5c7db9d39b' 
  AND token = 'Tj46N/3XOAZBi+k5MoTYD273a8KR4r5gU7PM19Qqsao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}