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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d3040ffd55f2a94114b1ae3d6c95d91f26bc544afaab39a14a3fce4f469010' 
  AND token = 'mg9a6yHTKwg5SdoGMYj4TjFGYtxsIHR0LpClgz1oQmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}