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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e61abd14ad49b78e00fe10b467e4f8407ef5a158eb631f0b59caa0df0b0e25a' 
  AND token = 'bBZJaBPEFb3ED1JBnawA4NY2qhrW2EvpzKbGqVhCiWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}