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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d68c6cefe481112d026d2f2d487d39414955bcc7869868c7207f4b3999e12be' 
  AND token = 'lLtrNi9UzJo9e8eC8C4sX2Z7UkRrHcfhH5xYsAqX3jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}