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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f525900e9ba61e44aa4dfcdf807b3ca94b4d8768a921f9502ac76e0abe25c9' 
  AND token = 'fupHlBaM19PRd26r6rPF24vDJNH2XSHGaGi6os8sNtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}