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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bd24a0af79550df80ed75cae3feeba8ca7e008e03d2a1f3d2e773018d3c476e' 
  AND token = 'kCf7UZPRIk+LQb/BXZPRmKzS7LOyFaExZjyaBJSFtF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}