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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1244be319f684f98858671b9ffa29ff2405af75b91cf91c586817f903d7dcf05' 
  AND token = '9yDnrnSOEcN+uVdiKNznPZY1iQ8/T7PDZYytqK95ldY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}