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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8989f8ab93c0302d882382d05534d171b1c9375e19c7fa43bc74cb968dc5a165' 
  AND token = 'lAvDXyu63zFOg5A1cekJ8EoTfXR0upGN3A3caUrr/eI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}