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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c6260797261de65c33f2e7466e52f73e7eb016fcc344d24b8e97964b711c16e' 
  AND token = '/PDK5NACrNm0Ju0o53k0TN1C4F1y21cOditAXC+PYh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}