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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e54fd7f037cc963f4de88e5df6f65c09f5d998c20437b6e80cf0e9802fb11d2' 
  AND token = '8kcsORSVUiv5C8fPWjnZ8ZuGJTALzZEC0E5zOs+sTCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}