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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f3c4e0e60c1ee17025f70872a8d4b87506672da2b486563531582b9545f9ece' 
  AND token = 's2NzXzgS3/NzDQwAJpb7XpO9kgVqImy+7fOnWJbQiFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}