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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a266fedce47fd592dbe1ec8ca7213dbb9bb6e3ca23a53c64101e711a0e6c0b41' 
  AND token = 'SULGlvGRDQzkCz1od45akD7ZbUtkdcBzet2zTF3l2Zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}