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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7173b9c79018e97b045fcea930356c39ff3fc882034b9b0c5f414f9d0d6baed3' 
  AND token = 'GT7INHzs4Ec9EUCYAYwIUdUm2wlCf29LCdfk3oQrr3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}