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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58822ba99fdd2c63925d321ac3944648c2845dafcee88a079ecd8f80909000da' 
  AND token = 'Pwx6Whmyyw0gOJF6T9B8xaFMFx/OQejKH9CqNdkLnTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}