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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73cc4e4146f80151e377cf07f70e79624f67ef2f31f78ddee7ea579e1c10a611' 
  AND token = 'C0KHUlgqEPNvypcPrDsx1GZsv5gfdj+AU+8y2H8jdz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}