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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0885f4422e2a2f52d3de45f46ac1773f00a71525fe2cb47b490e819db945d0a2' 
  AND token = 'hDCkDgnQWXoWUSDsEL2KGGmScKa2OhC5lN3BAouJepA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}