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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b46fe2b26726fb3719e25621747432a0bea9a98f4fc66db32947c78701d7232' 
  AND token = 'MkeHeKc7oAhmPLoDSv8cwdBDQrfztLHm1C9sD4x61UM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}