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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48c44981541b1358f885b3511730c2315ec36f432c059e0065064793ae79bd0b' 
  AND token = 'loORjnD06ZIAA5zOdGIzC/P1n0ETqbSjhasay67NHwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}