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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77385dcc763e7b758d099d63e1593ce00d20aa751d6079e61846364a0b90585d' 
  AND token = 'IfeiRC/iE50TVOxz/mjQ3ZjBtIwP+wvOrdyGq9bsyCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}