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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be4df1615b5cc81520c1678acc4d2615360ca62bd09820da7337af109797c405' 
  AND token = 'DWzVhkJ6mERNwjk6FZPtass+ZckIto1t1yaFca4Ddgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}