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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8210eb74b0fe6dd58ca5be107e0e79d43735b8f6417bad6120bd6e41db775711' 
  AND token = 'mKfOJQouG6g8GRLNVbvPy6Lks3eHHXhgmyE1G7IGAIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}