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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efa42bf8c1b7424e451ad0ce1ebaa13617b5335a530e1ab1eb884df80a14c3a4' 
  AND token = '4zmd8VBPquq2DPc9LCTKcj1UDJ4oHe1RmjhVq7QDql0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}