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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b980176cb08028e63ff36e4a0991b0d9fa0a4005c144c869698fa008ff2992ee' 
  AND token = '8ZlUDLEf3bSwV1F+POoYPCNr0Jg5NjBKOmh9JcUiOik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}