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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8d3a063b52708c334968321bb0cacc249ef931502b2ee1667932dae841c9d6' 
  AND token = 'FJUku2VjGxQKBXgiX/Ikc34loVQF7ys5PdGyvrQR2GM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}