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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e03319425aa84a7e46678a2e5c1f6b428fd685c6ee06f14b8dea695885e65a89' 
  AND token = 'L1SagexnsJwG7CY3k1r+/NpYb4uvBltn5wb9AgO0rCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}